ICSI – Intracytoplasmic Sperm Injection

 

 

Intracytoplasmic sperm injection (ICSI) is a process in which a single sperm with the aid of a device called a micromanipulator is injected into a single egg. Infertile couples with a severe male infertility factor can be treated with Intracytoplasmic Sperm injection (poor sperm count, motility or morphology). It’s extremely similar to IVF, which collects the gametes of the male and female partners (eggs and sperm). However, the difference is the way in which fertilization is achieved among these two procedures..

The ICSI procedure is done following a transvaginal oocyte extraction procedure, which takes one or more oocytes from a patient (an oocyte that is an egg) When eggs are collected, the male partner will give the sperm sample. The sample is tested in a lab and, should no sperm be found, the sperm from the epididymis or testis is extracted by a fertility specialist. Sperm extraction is also called Percutaneous Epididymal Sperm Suction (PESA) and Testicular Sperm Aspiration is also referred to as testicular sperm aspiration (TESA). When the couple chooses to use donor sperm, they come from a sperm bank, matching the male partner’s characteristics.

If you have any questions about intracytoplasmic sperm injection or would want to learn more about other alternative fertility treatment options in Malappuram, please contact Goodwill IVF. Our team is delighted to answer any questions or concerns you may have about beginning your road to parenting.

Why is it done ?

In the regular IVF procedure, the eggs and sperm are placed in the same dish together and “naturally” fertilization occurs in most cases. In many cases, however, the number of appropriate sperms can be limited or other factors can prevent fertilization, and therefore regular IVF is not the solution.  ICSI is the treatment of choice in such cases.

How do you Prepare ?

Procedure preparation is important for both partners as the best quality of eggs and sperm must be found for this procedure.

For women, the choice of a balanced diet and hydration during procedure is very important. Before starting treatment, exercise and physical activity are also recommended.

For men, the diet and the workout remain the same. In addition, it can be helpful to refrain from processed foods and to add a lot of fruits or vegetables to your daily diet.

It is also recommended to watch your BMI closely and not to use laptops on the lap as this will increase testes’ temperature and therefore decrease the quality of sperm.

What can you expect ?

The ICSI is very similar to the IVF cycle from the patient’s point of view, because the same steps are concerned. In particular, in the event of a very low count of sperm, or abnormal sperm motility, and a sperm removal from the epididymis (MESA/PESA), or tests, ICSI or Intra-Cytoplasmic Sperm Injection is required.

In certain cases, after electro-ejaculation, the TESE/TESA is also derived from the urine. An ICSI can also be performed if the semen contains high antibodies, and if fertilization attempts using the regular IVF method have been a previous failure.

As for insemination, ICSI needs one sperm cell per oocyte, whereas IVF needs 50-100 thousand in number. Mostly because in IVF, sperm needs to fertilize the egg on its own, whereas ICSI directly injects one sperm into a single egg. The fertilized egg or embryo is then transferred to the womb to develop further. Embryos may be grown for up to six days in the lab but transported two to four days from fertilization or for five days from the blastocyst stage after fertilization. A blastocyst transfer can improve your pregnancy chances.  Not more than two embryos are normally transmitted but you can also choose to transfer a single embryo also.

Post-procedure/ results

The average success rate of ICSI people after a single cycle is above IVF.

50 to 80% of the eggs will be fertilized in the ICSI procedure. It is a common assumption that fertilization occurs when the sperm is injected into an egg. This is debatable, because the levels of fertilization alone do not indicate a full-term pregnancy and live birth rates. For parents who have successfully tried IVF, ICSI is a good choice. Poor sperm motility or a hope to get pregnant after vasectomy can also be a decisive factor. ICSI’s success rates are usually higher than the IVF routine.

What risks are there ?

Multiple pregnancies result in the event that more than one embryo is transferred. OHSS (ovarian hyperstimulation syndrome) and ectopic pregnancy are the other risks. ICSI carry the same risks related to routine IVF.

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